TECNinox fermenter/bioreactor
Year of construction: 2015
Suitable for R&D, small batch production, pilot plant. Box of manuals
included.
Characteristics:
Fermenter head without sharp edges to improve cleaning, GMP gasket;
with TC connections of various sizes (3/4, ½, 1), usable for
additions, feeding, inoculation, etc.
Fermenter geometry: 3:1
Operational pressure range: -0.01 to 3. 00 bar g
Double mechanical seal
Impellers 3 Rushton / 3 Pitched Blade
Configurable motor speed: 50-1500 rpm
Motor position: overhead motor shaft, as close as possible to sparger
and bottom
Toroidal sparger with possibility of coupling and uncoupling
Exhaust gas condenser
Integrated CIP system
Working volume for 36L bioreactor: 20L, Minimum working volume 7.5L
(positioning holder for probes)
Working volume for 74L bioreactor: 50L, dependent on position of last
impeller
Exhaust gas management: double exhaust gas line after the outlet
filter (the gas line must divide into two branches: one direct to the
spent gas analysis system (airnova) and the other to the
drain/waste)
Inlet air from above and from the sparger, with flowmeter
Aeration: 0 to 2. 5 VVM
O2 inlet: 0 to 2.5 VVM, O2 inlet from above and from the sparger, with
flowmeter
N2 inlet: 0 to 1 VVM, N2 inlet from above and from the sparger, with
flowmeter
CO2 inlet: 0 to 1 VVM, CO2 inlet from above and from the sparger, with
flowmeter
Head pressure adjustment: automatic
Fixed speed pump with remote control
Bottom valve filter
Variable speed pumps, two bottom valves
Integrity test: integrated housing to perform in situ integrity
test
Loading soil hole for manual loading
Fixed speed Peristaltic pumping, position adjacent to bioreactor pH,
for control of acid/ base, CO2
Feeding base inlet via Sacova valve with ingold control
Requirements:
Electricity: 380v, 50Hz
Steam feed: 3 - 9 bar
Clean steam: 3 bar g
Purified water
Compressed air: 8 bar g
Refrigerated water: 9 - 12 deg C
Nitrogen: 8 bar
Oxygen: 12 bar
CO2: 8 bar
Softened water
Drainage and discharge
Italy
40141 Bologna 
